Nexgen AdderRx Review: Beware of these side effects (2021)

A bottle of AdderRx nootropic supplements.


AdderRx is an herbal nootropic supplement that is designed to improve focus. Unfortunately, this may come with some negative side effects.

AdderRx Ingredients

The most important part of taking a new drug is determining whether or not it’s safe for your body. No supplement is made precisely the same, and you never know when a particular ingredient can harm you. We recommend extra caution when dealing with nootropics because of how they can affect the brain and nervous system.


Dimethylethanolamine (DMAE) is an active ingredient in most nootropic supplements because its natural properties boost concentration and focus. It primarily slows down the build-up of amyloid plaque or “aging pigment,” which causes a gradual decline in mental sharpness. It also protects brain cells directly by embedding itself into a neuron and acting as an antioxidant.


Most people are familiar with this ingredient. The caffeine in the AdderRX formula promotes wakefulness, awareness, and enhanced mental focus. Most people can tolerate it and benefit from its properties; however, a supplement’s dosage needs to be measured precisely. Too low and the caffeine will have little effect; too high and it could make you anxious and irritable.


Theanine is an excellent substance to pair with caffeine because it has the opposite effect. While caffeine in substantial doses can cause anxiety or jitters, theanine levels out the worst symptoms of anxiety to allow individuals taking nootropic supplements to retain a “zen” state of mind. It has mild side effects, but, like caffeine, a theanine dosage must be measured carefully. The optimal level of theanine needed to get the most out of it is around 150mg — 300mg.

Synephrine HCL

Synephrine is an odd inclusion in AdderRx’s ingredients. It’s a powerful stimulant that elevates heart rate and the amount you sweat but has no known nootropic applications. Its potent effects are mainly due to it being the main ingredient in weight loss supplements.


CDP-Choline or Citicoline is a brain chemical that occurs naturally in the human body. It’s proven to be an ideal nootropic substance that enhances memory retention, mental focus, and information processing. Citicoline is often used as a treatment option for people diagnosed with dementia, Parkinson’s disease, and ADHD. There are few severe side effects associated with it, but you need to use a certain amount before seeing noticeable improvements in cognitive functions.


Like synephrine, hordenine is not a nootropic and is more likely to be found in weight loss supplements. Its effects run counter to what nootropics try to accomplish, keeping people who take it in a constant stressed state by preventing the breakdown of noradrenaline (the chemical in our brains that controls our fight-or-flight response).

AdderRx Dosage

AdderRx comes with 30 capsules in the bottle, with the instructions saying to take only one pill per day. The bottle has a warning printed on it, stating that you shouldn’t take more than two capsules in 24 hours.

AdderRx Side Effects

Most of the risks in taking AdderRx come from the lack of information on its ingredients’ dosage. The formula is mainly composed of chemical stimulants rather than more natural ingredients, and the combination of those substances makes the risk of side effects even more significant. Because people react differently to differently measured doses, we’ve provided a list of all the side effects that AdderRx’s ingredients could cause.


Depending on the person, DMAE can have wildly different effects. The most common side effects are increased blood pressure, upset stomach, headaches, confusion, drowsiness, and irritability. You should not take DMAE if you’re pregnant or have been diagnosed with bipolar disorder or epilepsy.


The side effect of caffeine are well known if you’ve ever had too much coffee. An abundance of caffeine in your system can cause insomnia, anxiety, heart palpitations, nausea, chest pain, and more.


Theanine is a beneficial amino acid with mild side effects such as headaches and drowsiness. It’s meant to counteract the effects of AdderRx’s stimulant ingredients, but without an exact dosage, it’s impossible to tell how effective it is.

Synephrine HCL

Synephrine is one of the more potent stimulants in AdderRx’s mixture and has serious side effects as a result. It can cause high blood pressure, stroke, and heart attack, particularly when used together with other stimulants like caffeine.


Citicoline can cause side effects such as headache, nausea, and dizziness in high doses. In low doses, the primary effects aren’t even noticeable.


Hordenine prevents the breakdown of noradrenaline and can keep you in a constantly stressed state. Other side effects include rapid heart rate and high blood pressure.

AdderRx vs. ADDtabz

NexGen Biolabs AdderRx and Gentech Pharmaceutical Addtabz are similar in almost all their ingredients. Their marketing advertises them both as adequate alternatives to Adderal, perfect for people diagnosed with ADHD, college students, and professionals. In reality, while AdderRx and ADDtabz can provide temporary cognitive improvement, it won’t be to the same level as Adderall and should not be used as a replacement.


Our conclusion on the NexGen Biolabs AdderRx supplement is that, while it does work to provide you with a cognitive boost, there are products available that do it better and more reliably. NexGen’s use of proprietary blends makes it unpredictable, so consumers don’t know how much of each ingredient they are putting in their bodies. This effect is made worse by the inclusion of several questionable or untested substances in the formula.


Can You Buy AdderRx in Stores?

Yes, AdderRx is an over-the-counter nootropic supplement. However, while it may work to keep a busy college student or young professional up in the morning, do not use it as a replacement for Adderal.

Can You Get AdderRx at Walmart?

Yes, you can purchase AdderxRx from Walmart’s physical pharmacies or online.

Can You Get AdderRx at Walgreens?

Yes, Walgreens is one of the largest drugstore chains, and they tend to carry supplements like AdderRX before smaller stores can.

Where To Buy AdderRx?

In all honesty, you’d probably find AdderRx in most supermarkets, drug stores, or anywhere that has a pharmacy. There are better options out there, but if you’re looking for an inexpensive stimulant like AdderRx to get through the day, then it’s best purchased through NexGen’s website. NexGen offers a percentage off your purchase if buying in bulk and a 30-day money-back guarantee.

Greg Don is an avid health and fitness enthusiast. When he isn't hiking or fishing outdoors, he also enjoys reading and writing about his passions.